SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549


                                  Schedule 13G

                    Under the Securities Exchange Act of 1934

                               (Amendment No. 5)*


                   Integra LifeSciences Holdings Corporation
                                (Name of Issuer)


                          Common stock, $.01 par value
                         (Title of Class of Securities)

                                    457985208
                                 (CUSIP Number)

                                December 31, 2007
             (Date of Event Which Requires Filing of this Statement)


         Check the appropriate box to designate the rule pursuant to which this
                                 Schedule is filed:

         [ ] Rule 13d-1(b)
         [ ] Rule 13d-1(c)
         [X] Rule 13d-1(d)

         *The remainder of this cover page shall be filled out for a reporting
         person's initial filing on this form with respect to the subject class
         of securities, and for any subsequent amendment containing information
         which would alter the disclosures provided in a prior cover page.

         The information required in the remainder of this cover page shall not
         be deemed to be "filed" for the purpose of Section 18 of the Securities
         Exchange Act of 1934 ("Act") or otherwise subject to the liabilities of
         that section of the Act but shall be subject to all other provisions of
         the Act (however, see the Notes).




Page 2 of 11 Pages - --------------------- CUSIP No. 457985208 13G - --------------------- - ------- ----------------------------------------------------------------------- 1 NAME OF REPORTING PERSON: Richard E. Caruso, Ph.D. I.R.S. IDENTIFICATION NO. OF ABOVE PERSON (entities only): - ------- ----------------------------------------------------------------------- 2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (See Instructions) (a) |X| (b) |_| - ------- ----------------------------------------------------------------------- 3 SEC USE ONLY - ------- ----------------------------------------------------------------------- 4 CITIZENSHIP OR PLACE OF ORGANIZATION United States - -------------------------------------------- ---- ----------------------------- NUMBER OF 5 SOLE VOTING POWER SHARES 78,071 shares* ---- ----------------------------- BENEFICIALLY 6 SHARED VOTING POWER OWNED BY 6,633,543* ---- ----------------------------- EACH 7 SOLE DISPOSITIVE POWER 78,071* REPORTING PERSON ---- ----------------------------- 8 SHARED DISPOSITIVE POWER WITH: 6,633,543* - ------------------------------------------------------------------------------- 9 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON 6,711,614 shares* - ------- ----------------------------------------------------------------------- 10 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES (See Instructions) - ------ ------------------------------------------------------------------------ 11 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9 25.5%* - ------- ----------------------------------------------------------------------- 12 TYPE OF REPORTING PERSON (See Instructions) IN - ------- ----------------------------------------------------------------------- *Includes 55,000 shares of common stock that may be acquired upon exercise of options as of or within 60 days of February 1, 2008. Dr. Caruso disclaims beneficial ownership of the shares owned by Tru St Partnership LP, Provco Leasing Corporation and The Uncommon Individual Foundation as described in this Schedule 13G (Amendment No. 5) except to the extent of his pecuniary interest therein.

Page 3 of 11 Pages - --------------------- CUSIP No. 457985208 13G - --------------------- - ------- ----------------------------------------------------------------------- 1 NAME OF REPORTING PERSON: Tru St Partnership LP I.R.S. IDENTIFICATION NO. OF ABOVE PERSON (entities only): - ------- ----------------------------------------------------------------------- 2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (See Instructions) (a) |X| (b) |_| - ------- ----------------------------------------------------------------------- 3 SEC USE ONLY - ------- ----------------------------------------------------------------------- 4 CITIZENSHIP OR PLACE OF ORGANIZATION Pennsylvania - -------------------------------------------- ---- ----------------------------- NUMBER OF 5 SOLE VOTING POWER SHARES 0 ---- ----------------------------- BENEFICIALLY 6 SHARED VOTING POWER OWNED BY 6,591,205 shares ---- ----------------------------- EACH 7 SOLE DISPOSITIVE POWER 0 REPORTING PERSON ---- ---------------------------- 8 SHARED DISPOSITIVE POWER WITH: 6,591,205 shares - ------- ----------------------------------------------------------------------- 9 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON 6,591,205 shares - ------- ----------------------------------------------------------------------- 10 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES (See Instructions) - ------- ----------------------------------------------------------------------- 11 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9 25.0% - ------- ----------------------------------------------------------------------- 12 TYPE OF REPORTING PERSON (See Instructions) PN - ------- -----------------------------------------------------------------------

Page 4 of 11 Pages - --------------------- CUSIP No. 457985208 13G - --------------------- - ------- ----------------------------------------------------------------------- 1 NAME OF REPORTING PERSON: Provco Leasing Corporation I.R.S. IDENTIFICATION NO. OF ABOVE PERSON (entities only): - ------- ----------------------------------------------------------------------- 2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (See Instructions) (a) |X| (b) |_| - ------- ----------------------------------------------------------------------- 3 SEC USE ONLY - ------- ----------------------------------------------------------------------- 4 CITIZENSHIP OR PLACE OF ORGANIZATION Delaware - -------------------------------------------- ---- ----------------------------- NUMBER OF 5 SOLE VOTING POWER SHARES 0 ---- ----------------------------- BENEFICIALLY 6 SHARED VOTING POWER OWNED BY 6,614,543 shares ---- ----------------------------- EACH 7 SOLE DISPOSITIVE POWER 0 REPORTING PERSON ---- ----------------------------- 8 SHARED DISPOSITIVE POWER WITH: 6,614,543 shares - ------- ----------------------------------------------------------------------- 9 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON 6,614,543 shares - ------- ----------------------------------------------------------------------- 10 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES (See Instructions) - ------- ----------------------------------------------------------------------- 11 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9 25.1% - ------- ----------------------------------------------------------------------- 12 TYPE OF REPORTING PERSON (See Instructions) CO - ------- -----------------------------------------------------------------------

Page 5 of 11 Pages - --------------------- CUSIP No. 457985208 13G - --------------------- - ------- ----------------------------------------------------------------------- 1 NAME OF REPORTING PERSON: The Uncommon Individual Foundation I.R.S. IDENTIFICATION NO. OF ABOVE PERSON (entities only): - ------- ----------------------------------------------------------------------- 2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (See Instructions) (a) |X| (b) |_| - ------- ----------------------------------------------------------------------- 3 SEC USE ONLY - ------- ----------------------------------------------------------------------- 4 CITIZENSHIP OR PLACE OF ORGANIZATION Pennsylvania - -------------------------------------------- ---- ----------------------------- NUMBER OF 5 SOLE VOTING POWER SHARES 0 ---- ----------------------------- BENEFICIALLY 6 SHARED VOTING POWER OWNED BY 19,000 shares ---- ----------------------------- EACH 7 SOLE DISPOSITIVE POWER 0 REPORTING PERSON ---- ----------------------------- 8 SHARED DISPOSITIVE POWER WITH: 19,000 shares - ------- ----------------------------------------------------------------------- 9 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON 19,000 shares - ------- ----------------------------------------------------------------------- 10 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES (See Instructions) - ------- ----------------------------------------------------------------------- 11 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9 0.072% - ------- ----------------------------------------------------------------------- 12 TYPE OF REPORTING PERSON (See Instructions) CO - ------- -----------------------------------------------------------------------

Page 6 of 11 Pages Item 1. (a) Name of Issuer: Integra LifeSciences Holdings Corporation (b) Address of Issuer's Principal Executive Offices: 311 Enterprise Drive, Plainsboro, New Jersey 08536 Item 2. (a) Name of Person Filing: See (c) below. (b) Address of Principal Business Office or, if none, Residence: See (c) below. (c) Citizenship: Richard E. Caruso Ph.D. 795 East Lancaster Ave., Suite 200 Villanova, Pennsylvania 19085 United States citizen Tru St Partnership LP 795 East Lancaster Ave., Suite 200 Villanova, Pennsylvania 19085 Pennsylvania limited partnership Provco Leasing Corporation 209B Baynard Building 3411 Silverside Road Wilmington, Delaware 19810 Delaware corporation The Uncommon Individual Foundation 795 East Lancaster Ave., Suite 204 Villanova, Pennsylvania 19085 Pennsylvania corporation (d) Title of Class of Securities: common stock, $.01 par value. (e) CUSIP Number: 457985208 Item 3. Not applicable. Item 4. Ownership: Provide the following information regarding the aggregate number and percentage of the class of securities of the issuer identified in Item 1. (a) Amount beneficially owned: As of December 31, 2007, Dr. Caruso may be deemed the beneficial owner of 6,711,614 shares of common stock. He individually holds 23,071 shares and holds options to purchase 55,000 shares of common stock that are exercisable within 60 days of February 1, 2008. Tru St Partnership LP ("Tru St") may be deemed the beneficial owner of 6,591,205 shares of common stock. Dr. Caruso is the president and sole director of Provco Leasing Corporation ("Provco Leasing"). Provco

Page 7 of 11 Pages Leasing is the corporate general partner of Tru St. Provco Leasing is also the beneficial owner of 23,338 shares of common stock. The Uncommon Individual Foundation is the beneficial owner of 19,000 shares of common stock. Dr. Caruso is the founder and chief executive officer of The Uncommon Individual Foundation. Dr. Caruso disclaims beneficial ownership of shares held by Tru St, Provco Leasing and The Uncommon Individual Foundation except to the extent of his pecuniary interest therein. (b) Percent of Class: Based on 26,363,053 shares of the Issuer's common stock outstanding as of November 5, 2007 as reported in the Issuer's Form 10-Q for the quarter ended September 20, 2007: Dr. Caruso may be deemed the beneficial owner of 25.5% of the Issuer's common stock; Tru St, may be deemed the beneficial owner of 25.0% of the Issuer's common stock; Provco Leasing may be deemed the beneficial owner of 25.1% of the Issuer's common stock and The Uncommon Individual Foundation may be deemed the beneficial owner of 0.072% of the Issuer's common stock. (c) The Reporting Persons have the power to vote or dispose of the number of shares as follows: (i) Sole power to vote or direct the vote. Dr. Caruso may be deemed to have sole power to vote or direct the vote of 78,071 shares of common stock based on his ownership of 23,071 shares and options to purchase 55,000 shares of common stock that are exercisable within 60 days of February 1, 2008. (ii) Shared power to vote or direct the vote. Dr. Caruso, Tru St, Provco Leasing and The Uncommon Individual Foundation may be deemed to share the power to vote or direct the vote with respect to 6,633,543 shares of common stock. Dr. Caruso and Tru St may be deemed to share the power to vote or direct the vote with respect to 6,591,205 shares of common stock. Dr. Caruso and Provco Leasing may be deemed to share the power to vote or direct the vote with respect to 6,614,543 shares of common stock. Dr. Caruso and The Uncommon Individual Foundation may be deemed to share the power to vote or direct the vote with respect to 19,000 shares of common stock. (iii) Sole power to dispose or direct the disposition. Dr. Caruso has sole power to dispose or control the disposition of 78,071 shares of common stock based on his ownership of 23,071 shares and options to purchase 55,000 shares of common stock that are exercisable within 60 days of February 1, 2008. (iv) Shared power to dispose or direct the disposition. Dr. Caruso, Tru St Provco Leasing and The Uncommon Individual Foundation may be deemed to have shared power to dispose of or shared power to direct the disposition of 6,633,543 shares of common stock. Dr. Caruso and Tru St may be deemed to have shared power to dispose of or shared power to direct the disposition of 6,591,205 shares of common stock. Dr. Caruso and Provco Leasing may be deemed to have shared power to dispose of or shared power to direct the disposition of 6,614,543 shares of common stock. Dr. Caruso and The Uncommon Individual Foundation may be deemed to have shared power to dispose of or direct the disposition of 19,000 shares of common stock.

Page 8 of 11 Pages Item 5. Ownership of Five Percent or less of a Class: Not applicable. Item 6. Ownership of More Than Five Percent on Behalf of Another Person: Not applicable Item 7. Identification and Classification of the Subsidiary which Acquired the Security Reported on by the Parent Holding Company: Not applicable Item 8. Identification and Classification of Members of the Group: Exhibit A attached hereto identifies each member of the group filing this Schedule 13G/A pursuant to Rule 13d-1(c). Item 9. Notice of Dissolution of Group: Not applicable Item 10. Certification: Not applicable. Signature After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct. Date: February 5, 2008 /s/ Richard E. Caruso, Ph.D. ------------------------------ Richard E. Caruso, Ph.D. TRU ST PARTNERSHIP LP PROVCO LEASING CORPORATION, GP By: /s/ Richard E. Caruso, Ph.D. ---------------------------- Its: President PROVCO LEASING CORPORATION By: /s/ Richard E. Caruso, Ph.D. ---------------------------- Its: President THE UNCOMMON INDIVIDUAL FOUNDATION By: /s/ Richard E. Caruso, Ph.D. ---------------------------- Its: President

Page 9 of 11 Pages Exhibit Index Exhibit Title Page No. Exhibit A Group Members 12 Exhibit B Joint Filing Agreement 13

Page 10 of 11 Pages EXHIBIT A Group Members Richard E. Caruso, Ph.D. Tru St Partnership LP Provco Leasing Corporation The Uncommon Individual Foundation

Page 11 of 11 Pages EXHIBIT B Joint Filing Agreement In accordance with Rule 13d-1(k) under the Securities Exchange Act of 1934, as amended, the persons named below agree to the joint filing on behalf of each of them of a Statement on Schedule 13G/A (including amendments thereto) with respect to the common stock, par value $.01 per share of Integra LifeSciences Holdings Corporation, and further agree that this Joint Filing Agreement be included as Exhibit to such joint filings. In evidence thereof, the undersigned, being duly authorized, have executed this Joint Filing Agreement this fifth day of February 2008. TRU ST PARTNERSHIP LP PROVOCO LEASING CORPORATION, GP By: /s/ Richard E. Caruos, Ph.D. By: /s/ Richard E. Caruso, Ph.D. ------------------------ ---------------------------- Its: President Richard E. Caruso, Ph.D. PROVCO LEASING CORPORATION By: /s/ Richard E. Caruso, Ph.D. ------------------------ Its: President THE UNCOMMON INDIVIDUAL FOUNDATION By: /s/ Richard E. Caruso, Ph.D. ---------------------------- Its: President