UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION

                             Washington, D.C. 20549

                                    FORM 8-K

                                 CURRENT REPORT
                       Pursuant to Section 13 or 15(d) of
                       the Securities Exchange Act of 1934

       Date of Report (Date of earliest event reported): October 26, 2005

                    INTEGRA LIFESCIENCES HOLDINGS CORPORATION
             (Exact name of Registrant as specified in its charter)



          Delaware                      0-26224                   51-0317849
(State or other jurisdiction of  (Commission File Number)     (I.R.S. Employer
 incorporation or organization)                              Identification No.)


                              311 Enterprise Drive
                              Plainsboro, NJ 08536
               (Address of principal executive offices) (Zip Code)

       Registrant's telephone number, including area code: (609) 275-0500

                                 Not Applicable
          (Former name or former address, if changed since last report)


Check the appropriate box below if the Form 8-K filing is intended to
simultaneously satisfy the filing obligation of the registrant under any of the
following provisions:

[ ] Written communications pursuant to Rule 425 under the Securities Act
    (17 CFR 230.425)

[ ] Soliciting material pursuant to Rule 14a-12 under the Exchange Act
    (17 CFR 240.14a-12)

[ ] Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchang
    Act (17 CFR 240.14d-2(b))

[ ] Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange
    Act (17 CFR 240.13e-4(c))


ITEM 1.01. ENTRY INTO A MATERIAL DEFINITVE AGREEMENT. FIRST AMENDMENT TO EMPLOYEE STOCK PURCHASE PLAN On October 26, 2005, the Board of Directors of Integra LifeSciences Holdings Corporation (the "Company") approved the First Amendment to the Company's Employee Stock Purchase Plan (the "Plan"), effective January 1, 2006. The amendment makes the following changes: (i) reducing the common stock purchase price discount under the Plan from 15% to 5%, (ii) eliminating the "look-back" provision for calculating the purchase price of common stock, (iii) removing the 60-day notice requirement for employees to surrender their options to purchase common stock under the Plan and (iv) allowing the Company to terminate the options to purchase common stock under the Plan in the event of a merger in which the Company is the surviving corporation. The amendment also makes certain administrative changes. A copy of the amendment is attached as Exhibit 10.1 to this Current Report on Form 8-K and is incorporated by reference into this Item. ITEM 9.01. FINANCIAL STATEMENTS AND EXHIBITS. (c) Exhibits. Exhibit Number Description of Exhibit - -------------- --------------------------- 10.1 First Amendment to the Company's Employee Stock Purchase Plan, dated October 26, 2005

SIGNATURES Pursuant to the requirements of the Securities Exchange Act of 1934, as amended, the Registrant has duly caused this report to be signed on its behalf by the undersigned, hereunto duly authorized. INTEGRA LIFESCIENCES HOLDINGS CORPORATION Date: November 1, 2005 By: /s/ Stuart M. Essig ----------------------------- Stuart M. Essig President and Chief Executive Officer

Exhibit Index Exhibit Number Description of Exhibit - -------------- --------------------------- 10.1 First Amendment to the Company's Employee Stock Purchase Plan, dated October 26, 2005

                             FIRST AMENDMENT TO THE
                        INTEGRA LIFESCIENCES CORPORATION
                          EMPLOYEE STOCK PURCHASE PLAN

     This  First  Amendment  (the  "Amendment")  to  the  Integra   LifeSciences
Corporation Employee Stock Purchase Plan (the "Plan"),  which was adopted by the
Compensation  Committee  of the  Board  of  Directors  of  Integra  LifeSciences
Holdings  Corporation (the "Company") on October 26, 2005 and shall be effective
January 1, 2006, amends the Plan as follows:

1.   The title of the Plan and Section 1 are hereby amended by deleting the text
     "Integra LifeSciences Corporation" and inserting "Integra LifeSciences
     Holdings Corporation" in place of the deleted text.

2.   Section 2 is hereby amended by deleting the text "Stock Option Committee"
     in the first sentence and inserting "Compensation Committee" in place of
     the deleted text.

3.   Section 5(a) is amended by deleting the third sentence thereof and
     substituting the following in place of the deleted text:

     "The term of the first option term shall be six (6) calendar months (or, in
     the Committee's discretion may be fewer than six (6) calendar months); the
     terms of the second and succeeding options shall be twelve (12) calendar
     months (from January 1 to December 31) unless sooner terminated pursuant to
     Section 9(h) (the "Option Term")."

4.   Section 8(a) is amended by deleting the second sentence thereof and
     substituting the following in place of the deleted text:

     "However, in order for such surrender to be effective for the Option Term,
     the employee's written notice must be received by the Company prior to the
     end of the Option Term, at such time and in such manner as the Company may
     require."

5.   Section 9(b) is hereby amended to read in its entirety as follows:

     "Option Price. The per share exercise price of an option shall be 95% of
     the per share fair market value of the Common Stock as of the Exercise Date
     for the Option Term. In making such determination, during such time as the
     Common Stock is listed upon an established stock exchange or exchanges, the
     per share "fair market value" shall be deemed to be the quoted closing
     price on the last business day before the Exercise Date. During such time
     as the Common Stock is not listed upon an established stock exchange, the
     per share fair market value shall be determined by the Committee by a
     method sanctioned by the Code, or rules and regulations thereunder. The
     fair market value per share is to be determined in accordance with Treas.
     Reg. Section 1.421-7(e) and 20.2031-2. Subject to the foregoing, the
     Committee in fixing the exercise price shall have full authority and be
     fully protected in doing so."



6.   Section 9(h) is amended by deleting the second and third sentence thereof
     and substituting the following in place of the deleted text:

     "Subject to any required action by the stockholders, in the event of a
     merger or consolidation of the Company with or into another company
     (whether or not the Company is the surviving entity) then in the discretion
     of the Committee either (i) each outstanding option shall pertain and apply
     to the securities to which a holder of the number of shares of Common Stock
     subject to the option would have been entitled, or (ii) each option shall
     terminate, provided that each employee granted an option under this Plan
     shall, in such event, have the right immediately prior to such merger or
     consolidation to exercise his or her option and such date shall be the end
     of the then Option Term. A dissolution or liquidation of the Company shall
     cause each outstanding option to terminate, provided that each employee
     granted an option under this Plan shall, in such event, have the right
     immediately prior to such dissolution or liquidation, to exercise his or
     her option and such date shall be the end of the then Option Term."


     IN WITNESS WHEREOF, the undersigned, a duly authorized officer of the
Company, has caused this Amendment to be executed on this 26th day of
October, 2005.


                                  INTEGRA LIFESCIENCES HOLDINGS CORPORATION



                                  By: /s/ Stuart M. Essig
                                  -----------------------------------
                                  Name:  Stuart M. Essig
                                  Title:  President and Chief Executive Officer