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  <xs:element id="iart_FDAApprovalOfPremarketApprovalMember" abstract="true" name="FDAApprovalOfPremarketApprovalMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="iart_BusinessCombinationContingentConsiderationNumberOfLiabilities" abstract="false" name="BusinessCombinationContingentConsiderationNumberOfLiabilities" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="xbrli:integerItemType"/>
  <xs:element id="iart_BusinessAcquisitionNumberOfContingentLiabilities" abstract="false" name="BusinessAcquisitionNumberOfContingentLiabilities" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:integerItemType"/>
  <xs:element id="iart_ShortTermInvestmentsFairValueDisclosure" abstract="false" name="ShortTermInvestmentsFairValueDisclosure" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="iart_MichaelMcBreenMember" abstract="true" name="MichaelMcBreenMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
</xs:schema>
